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Caryl, Undiagnosed Bio

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Hello!

I’m 24 years old and I think I’m starting to have the initial symptoms of Cushing’s, albeit not that florid.

It starting last year in late 2017 when I am 100% certain that my face is getting bigger, and that I found it harder to lose weight despite adequate exercise and caloric limitation.

Fat started to accumulate generally. I also experienced bowel problems for which doctors diagnosed as constipation.

I have normal blood pressure and normal 75g OGTT results.

The other thing that has come up last month is a bruise about 2cm initially and is now 4cm in diameter and simply does. Not. Heal. 🙁

My OB-GYN told me I have PCOS, and would like to start me on birth control pills.

I just want to know if it’s still possible that I’m in the early stages of Cushing’s. 🙁
Thank you

My symptoms:

– Acne (non-resolving)
– Bowel problems/ constipation
– Non-healing wound
– Occasional palpitations

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Hannah Cushing’s Bio (News Item)

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When Hannah Richards noticed she’d put on weight in 2023, she put it down to her comfortable lifestyle with her boyfriend, Nathan Baker.

The ‘happy and content’ pair had been enjoying date nights and cheeky takeaways together since meeting the year before. Really, a few extra pounds were no big deal.

But when the 28-year-old hit three-stone heavier and a healthcare worker told her she had a puffy ‘moon face’, the Norfolk local began feeling really ‘horrendous’.

Unable to stop the spiralling changes in her body, she sought help.

In March this year, Hannah was diagnosed with Cushing’s disease – a rare condition that can cause weight gain -and doctors suspect a benign brain tumour is the cause.

‘When they diagnosed me, I cried. I didn’t feel upset or shocked, I just felt really relieved,’ Hannah says.

‘It’s been going on for so long and I was like “I finally have answers and I know what’s happening to my body now”. I wasn’t just going crazy.’

Cushing’s is a rare condition caused by having too much cortisol hormone in your body and can lead to increased body fat and mood changes.

When Hannah first met Nathan, 33, everything had been going well. ‘During the early stages we were having more takeaways and doing nice things together,’ she explains.

‘You know when you get into a new relationship and you go out for food a lot and get takeaways a lot and you get comfortable.’

As she began to get a little heavier, people told her it was ‘comfort weight gain’ from being in a comfortable and loving relationship, but any attempts at losing it were futile.

‘I went back to the gym and ate healthier but nothing was helping, I just kept gaining,’ Hannah, a healthcare assistant, explains. ‘I started swimming. No matter what I was doing I wasn’t losing the weight.

‘It got to the point where I’d look back at old photos and I looked completely different. If I put that online on a dating app people would probably think I’m like a catfish.

‘I looked in the mirror and I’d get really teary, depressed and upset thinking “it’s just not who I am anymore”?’

She adds that her hormones were all over the place and she felt like she was going through menopause and all the changes that come along with it.

‘Everything changed, my body, my mental health and my personality. It’s really tough,’ she adds.

‘I started to get quite a lot of breathlessness and heart palpitations,’ she says.

She felt like she was gaining all her weight on her chest and belly, and got stretch marks between her thighs, as well as other symptoms.

‘I had a lot of hair growth on my arms and side burns, they come through quite dark. My knuckles get quite dark and swollen, too. I get a lot of dark circles under my armpits and round the back of my neck,’ she says.

Hannah even shares how she had what a medical colleague referred to as a ‘moon face’, referencing the weight gain in her face, and her ‘buffalo bump’ where she gained weight in her upper back.

It was this colleague who pushed Hannah, from Cromer, to get checked.

‘One of my colleagues actually said to me “have you heard of Cushing’s syndrome?” I was completely oblivious to it,’ Hannah recalls.

‘She said “I’m not being rude but your face has got puffier and you’re tiny from the back but from the front you’re on the larger scale. You should go to your GP”.’

It was then her GP referred her to an endocrinologist, and she was finally diagnosed with Cushing’s disease. Doctors suspect a benign tumour in her brain is to blame, and Hannah is awaiting an MRI scan to see if it’s in her pituitary or adrenal gland.

‘It turns out my pituitary gland is sending signals to my kidneys and it’s producing too many steroids, which affects your cortisol levels and your body and your hormones,’ Hannah explains.

They need to take a blood sample from [my pituitary gland] to just confirm it’s 100% Cushing’s. They need to confirm it’s from my pituitary gland and not my adrenal gland.’

Once this is confirmed, the healthcare worker will have to have brain surgery to remove the pituitary gland from her brain, and following that, she’ll have to be on steroids for the rest of her life.

‘After that, I’ll never get Cushing’s again, which is a really good thing,’ she says. ‘Even now I feel horrendous considering what I was before. I used to be quite petite and fit and active.’

This diagnosis hasn’t affected her relationship though, with her and Nathan now getting married in September 2026, after meeting back in 2022 on Tinder.

‘There’s so many things people are unaware of. It’s quite scary really,’ she adds. ‘You wouldn’t have thought something so small in your brain can change your body so much. It’s so important that people know about it.

‘Even if you do have the symptoms and you don’t have Cushing’s it could lead to something else you never thought it would be.

‘Get checked out because it’s your body you know what’s right and wrong. Don’t let anybody tell you differently because they are not in your body and they don’t know what’s normal to you.’

From https://metro.co.uk/2025/10/07/gained-weight-comfortable-relationship-thought-24350005/ (lots of ads, a couple typos and some misinformation.  “Cushing’s Disease” suggests that Hannah has been diagnosed with a pituitary tumor already – this article suggests that it could be either pituitary or adrenal.  She has been diagnosed with Cushing’s Syndrome so far.

If diagnosed with Cushing’s Disease, Hannah would have pituitary surgery NOT brain surgery.  She may not need to be on steroids for the rest of her life, either.)

Jennifer, Undiagnosed Bio

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Hello, I am a 33 yearl old female who has been living a nightmare for the last 5 years as I have seen my total health delcine before my eyes.

I have gained massive amounts of weight with no medical reason, my monthly cycle has left me, insomnia, severe depression and anxiety for no reason, infertility, allmy obesity is in my stomach and upper back, I have developed sleep apnea from having a thick neck, I have the infamous buffalo hump, hair loss of 50% of my hair, I cannot lose weight no matter what I do, I take these weird week spells where I cannote even get out of bed, hair has literally stopped growing on my legs and other areas of my body, except on my chin and abdomen where I do not want it to grow, my face is round and red and people who see me cannot believe this transformation my body has undertaken and I then have to hear how could have let myself go? If you would just stay on a diet longer than 2 weeks? I am glad that my children are not fat? I could go on and on the emotionally abuse I have had to enudre the last 5-6 years.

I have exercised and exercised to no improvement other than I feel exhausted, I eat a very strict diet, my Mother had to move over here with us because I no longer can care for my children and need her help. I have medical bills back in the states that are like science fiction.

I finally got diagnosed with hypothyroidism and still feel horrible, I have to take Toprol XL for heart palpitations without no explanation from where they are coming from it is so much easier for some physicians to keep just giving you pills instead of trying to figure out what is the root problem.

I now live in a foreign country where it is even harder on me, but I do have an appointment after 10 months with an Endocrinologist here in Doha tomorrow and on November 9th I have an appointment to go see a Cushings Expert in the UAE in Dubai his name is Dr. Taher so I will give an update after theses two visits.

Jennifer
Doha, Qatar

Update December 30, 2007

Hello My name is Jennifer and I am a 33 year old American living in Doha, Qatar (Middle-East), I was finally sent to Dubai and seen an Endocrinologist and he did an MRI and i have two pituitary tumors and he believes that I do have Cushings so he referred me to see Dr. Bill Ludlam, MD in Seatte in January 2008 to get further testing.

I know that there were something worng with me a long time ago but I never knew it was something as stealthy as this disease possibly, I have all the classical symptoms. Also the tesing is so so expensive in the States so I am waiting for the Qatari Governments approval for my medical expenses in Seattle.

I will giva another update soon.

Update May 28, 2008

My current update. I did go see Dr. Ludlam with no avail since my insurance would not pay for him but he did state that I needed further testing so after I left Washington I went to my friends house in Alaska just to have time to think since my husband and I are seperated.

I decided to go back home to West Virginia to be with my family for support and see a Doctor there bringing all my reports and scans to him from the Dr. in the Middle-East and Dr. Ludlmas suggestions.

I seen Dr Yakub and they did tests and all of them came back positive for Cushings my urine, salivory and blood several times came back positive and high for Cushings , also my MRI in January showed that my pituitary tumors are still there.

He is a good doctor and is located in Huntington West Virginia and he not only practices Endocrinology but he is also a Professor of Endocrinology at Marshall University School of Medicine. I will keep all of you updated and thank you so much for your support through this trying time in my life and I pray that all of the Cushies on this board get diagnosed, treated and healed.

Update July 10, 2008

I have finally got my diagnosis and I am heading to the University of Virgnia in Charloettesville on July 23rd! I will update what happens from there. I would also like to say thank you to Christi who has helaped me and talked to me through this difficult time.

Update September 19, 2008

Hello Everyone I am so sorry that it has taken me son long to get back with you I had my Inferior Petrosal Sinus Sampling done this week at the University of Virginia in Charlottesville and it is confirmed I have pituitary dependent Cushings and I am scheduled for surgery the first week of October with Dr. John Jane Jr. They are great at the University of Virginia and I am so thankful for them. I am hoping that someone will take me under their wing while I am getting ready for surgery and give me some advice. I would really appreciate the help.

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